Infertility Treatment

DIVF/DEM

Donated Germ Cell Therapy (DIVF)

The treatment method using donated female gametes (DIVF) has become one of the most successful methods of assisted reproduction in ISCARE clinics.

The treatment is intended for couples where one or both partners cannot use their own germ cells for fertilization.

Female infertility has many causes. If a woman has fertility problems, we can solve most of them in our clinics. The treatment program includes a number of methods, including fertilization of donated eggs with the sperm of the partner or the sperm of an anonymous donor.

What is the process of a female donor selection?

During the introductory interview, the recipient fills in a questionnaire about preferred characteristics of the donor. Based on this information, a suitable donor is selected with the consent of the recipient.

For the ISCARE team, one of the priorities is to choose a donor of the same phenotype as is the recipient. The phenotype represents a set of observable external traits and characteristics, it is an external manifestation of the genotype (genetic information). The basic parameters of selection also include compatibility with the blood type, height, weight, eye color, hair color and level of education. This is also the only information about the donor that we can provide to the recipient.

The waiting time for a suitable donor ranges from a few weeks to a few months, depending also on the recipient’s preferences. If we already have frozen eggs from a suitable donor, it is possible to start treatment almost immediately.

How does the treatment process work?

In the first step, the menstrual cycles of the donor and the recipient are synchronized. The recipient undergoes hormonal preparation individually tailored by our physician. On the day the eggs are extracted, they are fertilized by the partner’s sperm.

As part of this treatment method, we offer the following guarantee program:

  • Provided the partner’s seminogram is normal, we guarantee that at least two blastocysts (stem cell embryos) will be obtained.
  • If the donor experiences unforeseen insufficiency, we will promptly start searching for a new donor.

What is the treatment’s success rate?

during the first cycle, 60% to 70% of women become pregnant under the donated germ cell (DIVF) treatment. Success depends mainly on the age of the female recipient.

Treatment with donated eggs
Booking the date of the initial consultation
2 weeks

Choose the clinic in Bratislava or Martin and book the date by phone, e-mail or the order form. You can find the necessary contact details here : https://www.iscare.sk/en/contact/

Initial consultation with a physician
1 day

The initial consultation with us is free and non-binding. At the appointment, the couple consults their state of health with the physician, an IVF specialist. This is followed by both vaginal and ultrasound examinations. The partner will provide a sample of ejaculate for seminogram examination. Having evaluated the initial information, the physician shall propose an individual treatment plan. More information about the initial consultation can be found here: https://www.iscare.sk/en/our-services/infertility-treatment/ivf-story/

Examination of the couple / selection of the female donor
1 – 2 months

donor The treatment process starts with examinations of the woman (hormonal profile, ultrasound examination of the uterus and ovaries, genetics and other according to individual needs) and the man (seminogram, genetics, urological examination if necessary).
Female donor selection: Female donor selection follows the preferences and characteristics of the couple. During the initial interview, the recipient fills in a questionnaire with requirements, based on which a suitable donor is sought.

Hormonal stimulation of the female donor
13 – 16 days

The aim of the hormonal stimulation of the donor is the activation of several eggs in the ovaries, which are collected and fertilized by the partner’s sperm at maturity. The female partner does not undergo hormonal stimulation, she is only preparing for the embryo transfer.

Egg extraction and fertilization
1 – 5 days

On the day of egg extraction, the partner submits his ejaculate, which is then processed, and the sperm are used to fertilize the obtained eggs. More information about the egg extraction and fertilization can be found here:   https://www.iscare.sk/en/our-services/infertility-treatment/ivf-story/

Embryo transfer
1 day

The embryo is transferred via a thin catheter through the cervix directly into the uterine cavity of the recipient. The procedure is performed jointly by the physician and the embryologist who selects the most suitable embryo.
The procedure lasts about ten minutes and is painless. After the procedure, the patient can go home. More information about the embryo transfer can be found here : https://www.iscare.sk/en/our-services/infertility-treatment/ivf-story/

Pregnancy test
2 weeks

A pregnancy test is done two weeks after the transfer. The test is done at the clinic or at an outpatient gynecologist. If the test is positive, a follow-up ultrasound examination will be performed at the clinic after another two weeks. If the test is negative, our IVF specialist will recommend the couple how to proceed further.

Pregnancy confirmation
2-3 weeks

Two weeks after a positive pregnancy test result, the physician shall perform a follow-up ultrasound examination at the clinic. If all is well, from about the 12th week of pregnancy, the woman is referred to the care of her outpatient gynecologist.

Donor embryo transfer (DEM)

At ISCARE clinics, we can help solve fertility problems even for couples who do not have optimistic prospects for conceiving their own offspring. In the treatment method using donated embryos, high success rate in achieved with such couples.

Who is the treatment for?

  • Couples where both partners are infertile and need donated eggs and sperm.
  • Couples who are unable to conceive a viable embryo.
  • Couples whose IVF cycles from their own germ cells have repeatedly failed.

How does the treatment process work?

The preparation of the woman for the acceptance of a donated embryo proceeds according to the same standards as for the insertion of an embryo from one’s own germ cells.

Embryo selection is based on the recipient’s preferences as in donated egg therapy (DIVF). The selection of a sperm donor must meet equally strict criteria and is also anonymous. We select the most suitable embryos according to the parameters specified by the partners.

Treatment with donated embryos
Booking the date of the initial consultation
2 – 4 weeks

Choose the clinic in Bratislava or Martin and book the date by phone, e-mail or the order form. You can find the necessary contact details here : https://www.iscare.sk/en/contact/

Initial consultation with a physician
1 day

The initial consultation with us is free and non-binding. At the appointment, the couple consults their state of health with the physician, an IVF specialist. This is followed by both vaginal and ultrasound examinations. The partner will provide a sample of ejaculate for seminogram examination. Having evaluated the initial information, the physician shall propose an individual treatment plan. More information about the initial consultation can be found here: https://www.iscare.sk/en/our-services/infertility-treatment/ivf-story/

Examination of the couple / selection of the embryo
1 – 4 weeks

The treatment process starts with examinations of the woman (hormonal profile, ultrasound examination of the uterus and ovaries, genetics and other according to individual needs) and the man (seminogram, genetics, urological examination if necessary).
Embryo selection follows the couple’s preferences. The selection must meet strict criteria and is anonymous.

Hormonal preparation
16 – 20 days

The aim of this process is the hormonal preparation of the uterine lining for receiving the embryo. An individual treatment protocol is prepared by a physician specialized in IVF. The process of administering hormonal drugs will be explained in detail by the coordinator.

Embryo transfer
1 day

The embryo is transferred via a thin catheter through the cervix directly into the uterine cavity of the recipient. The procedure is performed jointly by the physician and the embryologist who selects the most suitable embryo. The procedure lasts about ten minutes and is painless. After the procedure, the patient can go home.

Pregnancy test
2 weeks

A pregnancy test is done two weeks after the transfer. The test is done at the clinic or at an outpatient gynecologist. If the test is positive, a follow-up ultrasound examination will be performed at the clinic after another two weeks. If the test is negative, our IVF specialist will recommend the couple how to proceed further

Pregnancy confirmation
2-3 weeks

Two weeks after a positive pregnancy test result, the physician shall perform a follow-up ultrasound examination at the clinic. If all is well, from about the 12th week of pregnancy, the woman is referred to the care of her outpatient gynecologist.

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